Posts Tagged ‘C-PTSD’

Come out of the shadows,,, live in this present moment,

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“You think the shadow is the substance.”
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-”Rumi”-
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The “Ego” is an impersonator, only an identifier, a shadow.
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Happiness is not found externally, keep searching

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“Remember, the entrance door to the sanctuary is inside you.“ *
-Rumi-
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Below the ego, below judgment and thought lies the sanctuary.
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Empty your mind and take a peek!
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Off switch’ for pain discovered: Activating the adenosine A3 receptor subtype is key to powerful pain relief

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Saint Louis University Medical Center
Summary:
A way to block a pain pathway in animal models of chronic neuropathic pain has been discovered by researchers, suggesting a promising new approach to pain relief.
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In research published in the medical journal Brain, Saint Louis University researcher Daniela Salvemini, Ph.D. and colleagues within SLU, the National Institutes of Health (NIH) and other academic institutions have discovered a way to block a pain pathway in animal models of chronic neuropathic pain including pain caused by chemotherapeutic agents and bone cancer pain suggesting a promising new approach to pain relief.
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The scientific efforts led by Salvemini, who is professor of pharmacological and physiological sciences at SLU, demonstrated that turning on a receptor in the brain and spinal cord counteracts chronic nerve pain in male and female rodents. Activating the A3 receptor — either by its native chemical stimulator, the small molecule adenosine, or by powerful synthetic small molecule drugs invented at the NIH — prevents or reverses pain that develops slowly from nerve damage without causing analgesic tolerance or intrinsic reward (unlike opioids).
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A Key to Pain Relief
In this research, Salvemini and colleagues have demonstrated that activation of the A3 adenosine receptor subtype is key in mediating the pain relieving effects of adenosine.
“It has long been appreciated that harnessing the potent pain-killing effects of adenosine could provide a breakthrough step towards an effective treatment for chronic pain,” Salvemini said. “Our findings suggest that this goal may be achieved by focusing future work on the A3AR pathway, in particular, as its activation provides robust pain reduction across several types of pain.”
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Researchers are excited to note that A3AR agonists are already in advanced clinical trials as anti-inflammatory and anticancer agents and show good safety profiles. “These studies suggest that A3AR activation by highly selective small molecular weight A3AR agonists such as MRS5698 activates a pain-reducing pathway supporting the idea that we could develop A3AR agonists as possible new therapeutics to treat chronic pain,” Salvemini said.
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Excerpt From: Musashi, Miyamoto. “A Book of Five Rings….. . .“THE BOOK OF THE VOID”

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This is the greatest Samurai that ever walked the island of Japan, undefeated in over 62 duels plus two wars.
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“What is called the spirit of the void is where there is nothing.
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It is not included in man’s knowledge.
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Of course the void is nothingness.
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By knowing things that exist, you can know that which does not exist.
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That is the void.
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People in this world look at things mistakenly, and think that what they do not understand must be the void. This is not the true void. It is bewilderment.”
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*my two cents.
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“It is not included in mans knowledge”: The void is an intuitive space, a space where cognition and ego are non-existent, a void.
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By knowing that thought and judgment permeate the mind incessantly, there also must be a place of calm, peace of mind, emptiness.
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Maybe that is the void!
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What is Immediate, simple, concrete, repeatable, indestructible?

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Our focus object, the breathing track model.
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If We were to construct the perfect model for meditating, these are the important traits.
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Please give this a try, first with eyes open, following the breath.
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Internal dialogue, self talk,,,,,,, how do we change a PTSD sufferers negative self talk, image?bh

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Edward Bourne: self-talk;
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“It is so automatic and subtle you don’t notice it or the effect it has on your moods and feelings. It appears in telegraphic form- one short word or image (”Oh no!) contains a whole series of thoughts, memories, or associations.”
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How do we change this?
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Affirmations combined with a mindfulness practice.
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Yes, self image, self worth and how we talk internally are connected, interdependent on each other.
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I strive with all out effort to let go of judgment and to accept myself and my situation in life totally, bringing awareness and peace of mind to my spirit.
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Record, repeat, say out loud each morning, noon and night.
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Small, daily practices, change the mind, alter its negative functioning drastically.
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Another, very simple, concrete, immediate action that alters connections, structure in the brain. Grey matter density and volume can increase or decrease.
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We have enormous power to influency the way the brain/mind is wired and functions.
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Sedentary is closer to suffering, death: ,,,, action, life and living!i

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I don’t regret the things I’ve done,
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I regret the things I didn’t do
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when I had the chance.”
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– Unknown_. Probably a PTSD sufferer.
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Accept, focus, let go, be present, take some action, live.
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